The effect of imbalance data mitigation techniques on cardiovascular disease prediction
Keywords:
Imbalance dataset, Cardiovascular disease prediction, SMOTE-TOMEK, Marchine learning, Overfitting and UnderfittingAbstract
The prevalence of class imbalance is a common challenge in medical datasets, which can adversely affect the performance of machine learning models. This paper explores how several data imbalance mitigation techniques affect the performance of cardiovascular disease prediction. This study applied various data balancing techniques on a real-life cardiovascular disease (CVD) dataset of 1000 patient records with 14 features obtained from the University of Abuja Teaching Hospital Nigeria to address this problem. The data balancing techniques used include random under-sampling, Synthetic Minority Over-sampling Technique (SMOTE), Synthetic Minority Oversampling-Edited Nearest Neighbour (SMOTE-ENN), and the combination of SMOTE and Tomek Links undersampling (SMOTE-TOMEK). After applying these techniques, their performance was evaluated on seven machine learning models, including Random Forest, XGBoost, LightGBM, Gradient Boosting, K-Nearest Neighbours, Decision Tree, and Support Vector Machine. The evaluation metrics used are precision, recall, F1-score, accuracy, and receiver operating characteristic-area under the curve (ROC-AUC). Learning curve plots were also used to showcase the impact of the different data balancing techniques on the challenges of overfitting and underfitting. The results showed that the application of data balancing techniques significantly enhances the performance of machine learning models in heart disease prediction and effectively addresses the challenges of overfitting and underfitting with SMOTE-TOMEK, yielding the best-balanced fit as well as the highest precision, recall, F1-score, accuracy of 92%, and ROC-AUC of 96% on the Lightweight Gradient Boosting Machine (LightGBM) model. These results underscore the critical role of data balancing in predictive modelling for heart disease and highlight the effectiveness of specific techniques and models in achieving accurate, more reliable, and generalised predictions.
Published
How to Cite
Issue
Section
Copyright (c) 2025 Raphael Ozighor Enihe, Rajesh Prasad, Francisca Nonyelum Ogwueleka, Fatimah Binta Abdullahi

This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
Similar Articles
- Bolarinwa Bolaji, Abdullahi Ibrahim, Favour Ani, Benjamin Omede, Godwin Acheneje, A model for the control of transmission dynamics of human monkeypox disease in Sub-Saharan Africa , Journal of the Nigerian Society of Physical Sciences: Volume 6, Issue 2, May 2024
- Nour Hamad Abu Afouna, Majid Khan Majahar Ali, Optimizing precision farming: enhancing machine learning efficiency with robust regression techniques in high-dimensional data , Journal of the Nigerian Society of Physical Sciences: Volume 7, Issue 1, February 2025
- A. E. Ibor, D. O. Egete, A. O. Otiko, D. U. Ashishie, Detecting network intrusions in cyber-physical systems using deep autoencoder-based dimensionality reduction approach anddeep neural networks , Journal of the Nigerian Society of Physical Sciences: Volume 7, Issue 3, August 2025
- Ogechi Regina Amanso, Jeconia Okelo Abonyo, Phineas Roy Kiogora, Obiora Cornelius Collins, A novel mathematical model for transmission dynamics of HPV and cervical cancer progression with cancer-reliant awareness , Journal of the Nigerian Society of Physical Sciences: Volume 8, Issue 2, May 2026
- Danat Nanle Tanko, Farah Aini Abdullah, Majid K. M Ali, Matthew O. Adewole, James Andrawus, Onchocerciasis control via Caputo-Fabrizio fractional dynamics: a focus on early treatment and vector management strategies , Journal of the Nigerian Society of Physical Sciences: Volume 8, Issue 1, February 2026
- Hamza Abubakar, Abdu Sagir Masanawa, Surajo Yusuf, G. I. Boaku, Optimal representation to High Order Random Boolean kSatisability via Election Algorithm as Heuristic Search Approach in Hopeld Neural Networks , Journal of the Nigerian Society of Physical Sciences: Volume 3, Issue 3, August 2021
- Charles Otobrise, Godwin Eferurhobo, Prediction of the acentric factor of some halogenated hydrocarbons via group contribution techniques , Journal of the Nigerian Society of Physical Sciences: Volume 6, Issue 4, November 2024
- Josephine E. Ochigbo, Joel N. Ndam, Wipuni U. Sirisena, Optimal control with the effects of ivermectin and live stock availability on malaria transmission , Journal of the Nigerian Society of Physical Sciences: Volume 6, Issue 3, August 2024
- Umaru C. Obini, Chukwu Jeremiah, Sylvester A. Igwe, Development of a machine learning based fileless malware filter system for cyber-security , Journal of the Nigerian Society of Physical Sciences: Volume 6, Issue 4, November 2024
- B. C. Asogwa, O. M. Mac-kalunta, J. I. Iheanyichukwu, I. E. Otuokere, K. Nnochirionye, Sonochemical synthesis, characterization, and ADMET studies of Fe (II) and Cu (II) nano-sized complexes of trimethoprim , Journal of the Nigerian Society of Physical Sciences: Volume 6, Issue 3, August 2024
You may also start an advanced similarity search for this article.
Most read articles by the same author(s)
- Muhammad Musa Liman, Rajesh Prasad, Hauwa Ahmad Amshi, Feature-optimized hybrid CNN–ViT architecture for sustainable vision-based condition assessment in agriculture , Journal of the Nigerian Society of Physical Sciences: Volume 8, Issue 2, May 2026

